As acknowledged, issue that has to be given top priority by a country
for the continuance of its existence. Nations have always to watch out
for all kinds of internal and external threats, assaults, risks of wars
and terrorist actions. This is why they allocate a great part of their
official budgets to defense. Armies are provided with the most advanced
aircraft, ships, and arms, and the forces of defense are always kept at
the highest level of preparedness.
The human body is surrounded by a great number of enemies and threats.
These enemies are bacteria, viruses, and similar microscopic organisms.
They exist everywhere; in the air we inhale, the water we drink, the food
we eat, and the environment in which we live.
What most people are not aware of is that the human body has an excellent
army, the immune system, which fights against enemies. This is a real
army made up of many "soldiers" and "officials" with different assignments,
who are specially trained, employ high technology and fight with conventional
and chemical weapons.
Every day, even every minute, a permanent war is fought between this
army and the enemy forces, but away from our knowledge. This war can also
be in the form of minor, local skirmishes as well as battles in which
the whole body is involved and alarmed. We call these battles "diseases".
The general conduct of this war almost never changes. The enemy attempts
to fool the other side by camouflaging itself when intruding into the
body. The trained investigative forces are assigned by the defense to
identify the enemies. The enemies are identified and appropriate weapons
are produced to exterminate them. Then there is close contact, the defeat
of the enemy, cease-fire, and clearance of the battleground. Last, there
is storage of every type of information about the enemy as a precaution
against the possibility of a later attack....
Now let us examine this interesting war closer.
The Besieged Castle: The Human Body
We can liken the human body to a castle besieged by enemies. The enemies
look for various ways to invade this castle. The human skin is the wall
of this castle.
The substance of keratin in the cells of the skin is an impassable barrier
for bacteria and fungi. Foreign substances that reach the skin cannot
pass through this wall. Moreover, although the outer layer of skin that
contains keratin is continuously rubbed off, it is renewed by skin growing
from beneath. Thus, all unwanted guests that have squeezed between the
skin are ejected from the body together with dead skins, during renewal
of the skin from inwards to outwards. The enemy can only make its way
in through a wound that is inflicted on the skin.
The Front Line
One of the ways through which viruses enter the body is air. The enemy
pushes its way to the body through the air inhaled. However, a special
secretion in the nasal mucous membrane and cell-swallowing defense elements
in the lungs (phagocytes) meet these enemies and take control of the situation
before the danger grows. Digestive enzymes in the stomach acid and small
intestine eliminate a great number of the microbes that seek to enter
the body through food.
The Clash of the Enemies
There are some microbes that have settled in various parts of the human
body (such as skin, skin folds, mouth, nose, eye, upper respiratory canals,
digestive canal, the genitals) yet do not cause illness.
When a foreign microbe enters the body, these domestic microbes - thinking
that their habitation would be invaded- and not wishing to give way to
the foreigners who invade their habitation - fight strenuously. We can
define them as professional soldiers. They try to protect their territory
for their own ends. Thus, the complex army in our body is reinforced by
these micro supports.
Step by Step to Hot War
If a microscopic intruder entering the body can overcome defense elements
on guard and bacteria serving as soldiers, it causes war to begin with.
After that, the body, with its ordered army, fights a perfect offence-defense
war against this foreign army.
The war fought by the defense system is comprised of four parts:
1. Identification of the enemy.
2. The fortification of defenses and the preparation of offensive
weapons.
3. Attack and battle.
4. Retreat to normal state.
The cells that first meet the enemy units are macrophage cells that
make "phagocytosis", i.e., that engulf the enemy. These cells are involved
in close contact with the enemy, and fight a hand-to-hand war. They are
just like infantrymen who fight a bayonet war against enemy units and
struggle at the distant front line of the army.
Moreover, macrophages function as intelligence units, or as the secret
service of an army. They hold one portion of the enemy they destroy. This
portion is used to identify the enemy’s identity and to determine
its features. Macrophages pass this portion to another intelligence unit,
messenger-T cells.
General Alarm
When a country is involved in war, a general mobilization is declared.
Most of the natural resources and the budget are spent on war expenses.
The economy is re-arranged according to this extraordinary situation and
the country is involved in total action. In a war, which the defensive
army of the body will fight as a whole, mobilization is also declared.
Do you wonder how?
If the enemy is more than they can handle, the cavalcades (macrophages)
that launch an attack secrete a special substance. The name of this substance
is "pyrogen" and it is a kind of alarm call. After travelling a long way,
"pyrogen" reaches the brain and stimulates the fever-increasing centre
of the brain. Following this stimulation, the brain sets off alarms in
the body and the person develops a high fever. The patient with a high
fever naturally feels a need to rest. Thus, the energy needed by the defense
army is not spent elsewhere. As seen, there exists an extremely complex
plan and design at work.
The Ordered Army Swings into Action
The war between the microscopic intruder and the immune system becomes
more complicated after mobilization, that is, your falling ill in bed.
At this stage, infantrymen (phagocytes) and cavalrymen (macrophages) have
proved insufficient, the whole body is alarmed, and the war becomes heated.
At this stage, lymphocytes - (T and B cells) - intervene.
Cavalrymen (macrophages) pass the information they have on the enemy
to T helper cells. These cells summon T cytotoxic and B cells to the battleground.
These are the most effective fighters of the immune system.
Weaponry Production
As soon as B cells receive information about the enemy, they start producing
weapons. These weapons, just like ballistic missiles, are only produced
to hit the enemy on whom information is available. This production is
so perfect that the three dimensional structure of the microscopic intruder
and the three dimensional structure of the weapon fully match each other.
This accord is like that between a key and its lock.
Antibodies advance towards the enemy and clamp tightly on it. After
this stage, the enemy is neutralized like a tank that has its treads,
cannon and gun destroyed. Afterwards, other members of the immune system
come and eliminate the neutralized enemy.
Here, there is a very important point to consider: there are millions
of types of enemy that the immune system will confront. B cells can produce
an appropriate weapon for all types of enemy no matter what they are.
This means that the immune system innately has the knowledge and capability
to produce the keys appropriate to millions of different types of locks.
These unconscious cells have the ability to make millions of types of
antibodies, and their using it in the best way proves the existence of
a creation by the Owner of an exalted power.
Furthermore, the system is more sophisticated. As B cells destroy the
enemy with ballistic weapons, T cytotoxic cells also fight a tough war
against the enemy. When some viruses enter a cell, they can hide from
the weapons produced by the B cells. The T cytotoxic cells find the diseased
cells in which this camouflaged enemy hides and destroy them.
After the Victory
After the enemy is defeated, the T suppressor cells swing into action.
These cells give the army of defense the command to cease fire, and cause
the T cytotoxic and B cells to stop their activities. Thus, the body does
not carry on in a state of mobilization in vain. After the war is over,
most of the T and B cells produced specifically for the war complete their
lifecycle and die. This tough war, however, is not to be forgotten. Before
the war, a short time passed while the enemy was identified and the necessary
preparations made. If the enemy ever comes back, the body will be much
better prepared. A group of memory cells, which have come to know the
features of the enemy, will constantly serve in the immune system in future.
In a possible second attack, the immune system, with the information in
the memory cells, will have the means to react before the enemy gains
force. The reason why we do not catch mumps or measles again, after we
have once caught them, is because of the memory of our immune system.
Who is He Who Creates the System?
After all the information we have examined, we have to take our time
and think about how this perfect immune system to which we owe our lives
has come to exist. There is a flawless plan at work. Everything needed
for the operation of this plan is intact: macrophages, the pyrogen substance,
the fever raising centre of the brain, the body’s fever raising
mechanisms, B cells, T cells, weapons... How, then, has this perfect system
come into being?
Not surprisingly, the theory of evolution, which proposes that living
beings have come into being by coincidence, cannot explain how this complex
system came about. The claim of the theory of evolution is that living
beings and living systems have originated step-by-step by the accumulation
of little coincidences. However, the immune system cannot by any means
have originated "step-by-step". The reason is that in the case of the
absence or malfunction of even one of the factors that make up the system,
the system cannot work and the person could not survive. The system must
have come into being completely and flawlessly with all its components
intact. This reality renders the notion of "coincidence" meaningless.
Who, then, makes this plan? Who knows that the body’s fever must
rise, and that only that way the energy needed by the army of defense
will not be spent elsewhere? Is it the macrophages? Macrophages are merely
tiny cells. They do not have the capacity to think. They are living organisms
that obey an established superior order and that fulfill their duties.
Is it man? Certainly not. People are not even aware that such a perfect
system is at work in their own bodies. However, this system, of which
we are unaware, protects us from certain death.
It is obvious that the one who created the immune system, and who created
the whole human body, should be a Creator Who has exalted knowledge and
might. This Creator is Allah, Who has created the human body from a "drop
of fluid".
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The front defense line of the body is the skin. When a cut or wound
is inflicted on the skin, it means that the body is in danger. Viruses
and bacteria can easily make their way through. When such a wound
is inflicted, "virus- and bacteria-hostile" cells called "phagocytes",
rush to the afflicted spot and try to swallow the micro-organisms
that intrude into the body. On the other hand, the wound on the skin
has long since started to receive treatment to prevent further foreign
materials from entering the body. |
| "THE CELL INVASION" OPERATION OF
THE VIRUS
1. Virus contacts the cell it approaches and adheres to its surface.
(It is seen on a bacteria cell in the scheme).
2. The virus discharges a special enzyme at the point of contact
that will help melt the membrane of the cell it approaches. Because
of this action, a hole forms in the cell wall. The virus pulls back
its tail and, by shrinking, it injects the nucleic acid in its body
(DNA or RNA) into the cell.
3. The nucleic acid of the virus that enters in the cell takes
it under control. The vital functions of the cell stop. The nucleic
acid of the virus self-replicates by using the resources of the
cell.
4. The newly formed parts of the virus come together and form
new viruses.
5. When sufficient viruses are formed, the cell bursts and developed
viruses swing into action to find new host cells. The time from
the virus’ intrusion into a cell to the end of its reproduction
is around 20-25 minutes. At the end of each replication, 200-300
new viruses are formed in a host cell.
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| Macrophages are those
elements of the immune system that fight at the front. They engulf
and digest all kinds of foreign substances in the blood. Their other
task is to call the T cells for help wherever they meet the enemy.
In the photograph on the left, a macrophage is seen trying to catch
a bacterium with its extensions. On the right, the macrophage is trying
to engulf a lipid molecule that has entered the body. |
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THE IMMUNE SYSTEM
The leucocytes, around a trillion in number, form a highly specialized
army of defense. The most important agents of this army and the
duties they perform during a war with the enemy are described below.
The Virus
The virus, a genetic data package, is dependent on the environment
to be activated. It has to use the mechanisms of a host cell in
order to reproduce.
The Macrophage
It is a watchman and the defense cell in the front line. It engulfs
and digests all kinds of foreign materials in the blood. When it
runs into a microscopic intruder, it summons up T helper cells to
the site of action.
The T Helper Cell
It is the administrator of the immune system. After identifying
the enemy, it goes to the spleen and lymphatic glands and warns
other cells to fight against the agent of disease.
T Cytotoxic Cells
Warned by the T helper cell, these cells destroy the cells that
are occupied by foreign materials and cancer cells.
The B Cell
These cells, considered as biological weapon factories, are found
in the spleen and the lymphatic glands. When warned by T helper
cells, they produce strong chemical weapons named antibodies.
Antibodies
This protein in the shape of a "Y" sticks onto the disease
agent, renders it ineffective and turns it into a target for killer
cells.
The T Suppressor Cells
This third type of the T cells slows the activities of the T and
B cells or stops them. It ends the assault after the illness has
been overcome.
The Memory Cell
This defense cell is formed after the first disease is over. By
remaining in the body for years, it ensures that the immunity mechanism
is activated very rapidly and effectively when the body meets an
agent of the same disease again.
1)The War Begins
When viruses are disseminated in the body, some of them are engulfed
by the macrophages. Macrophages split the antibodies off the virus
and stick them onto their own surface. Very few out of millions
of T helper cells traveling in the circulatory system have the ability
to "read" this specific antibody. These particular T cells which
stick on the macrophage become active.
2)Defense Cells Increase
When T helper cells are activated, they tend to increase. They
then warn the T cytotoxic cells and B cells, which are few in number
and sensitive towards the enemy virus. While the number of B cells
increases, the T helper cells give them the signal to produce antibodies.
3)The Defeat of the Disease
Meanwhile, some of the viruses have entered the cells. Viruses
can only replicate within a cell. With the chemical materials they
secrete, T cytotoxic cells cause the death of these cells by drilling
through their membranes, thus preventing the virus in the cell from
reproducing. By holding ectly onto the surface of the virus, antibodies
neutralise it, prevent it from entering the cells and start chemical
reactions that will destroy the invaded cells.
4)After the War
After the disease is won, T suppressor cells stop the whole offensive
system. Memory-T and B cells remain in the blood and lymphatic system
in order to become immediately activated in case a virus of the
same type is met.
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